The Minister of Science, Technology and Innovation,
Dr. Monica Musenero has defended the cost of mice that are going to aid the process of
developing a Covid-19 vaccine in Uganda.
Musenero who is facing a parliamentary investigation over the management of 31 billion Shillings initially appropriated for the
vaccine development process, on Friday appeared before the Select Committee of
Parliament to provide accountability for the funds.
The investigation stems from documentary evidence tabled before Parliament
recently by Ntungamo Municipality MP Yona Musinguzi seeking to implicate
Musenero regarding the utilization of funds meant to facilitate the COVID-19
Musinguzi demanded accountability for funds so far
released towards the development of a vaccine under the Presidential Scientific
Initiative on Epidemics-PRESIDE, a brainchild of President Yoweri Museveni led
by Dr. Musenero, who was a Presidential Advisor on Epidemics at the time it was
Both Musinguzi and
Musenero appeared before the Select Committee last week but a session between
MPs and the Minister was closed to journalists upon request by Musenero over
sensitivity of the ongoing research.
Select Committee meeting was dedicated to purely accountability of the funds
and the Minister was tasked by Butambala Woman MP, Aisha Kabanda to explain the
8 million Shillings dedicated to procuring a single mouse.
follows Musenero’s revelation to MPs last week that one of the vaccines being
developed is at stage 7 and that they have mice, where mouse costs
8 million Shillings because they are very special.
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In response, Musenero
said that the mice are very high technology animals and they will need them
together with the necessary facilities to enable the quick development of the vaccine.
She said that 8 million Shillings for each mouse is on the cheaper side and
called upon Prof. Enock Matovu from Makerere University’s Department of
Veterinary to explain further about the mice.
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Prof. Enock Matovu
further explained that the mice in question have been genetically modified in high-tech
processes and are not susceptible to Covid-19.
“So what science has
done, is to go into the laboratory and genetically engineer these mice, introduce
a part from the human genomes that makes us susceptible… via which the virus
enters into our cells, and they have put it into that mouse to make it a model
which you can use to study disease,” Prof. Matovu explained in part.
He further said that
this is because scientists need something that gets symptoms of coronavirus
disease so that they challenge it with the virus, vaccinate it and find out
whether the developed vaccine is efficacious.
Prof. Matovu said
that the cost for each mouse is high because at purchase, they are provided a
license to propagate them.
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Tony Awany, the
Select Committee acting Chairperson and MP Kabanda further asked about the scientific
name of the mice and the purchase order conditions.
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In response, Prof.
Matovu said that they have ordered for only four mice and these will come with a
license allowing Uganda to propagate them locally.
He said that in total, they
will need a total of 200 mice to test one vaccine.
“We can produce
thousands of these mice as long as we are operating within the limits of this
agreement," explained Prof, Matovu. "The mouse multiplies pretty fast and the central research animal
facility we have ensures bio-safety and they cannot escape. Secondly, they are
a little bit delicate; they cannot survive on their own like in other ordinary
He said that the
strain being procured is BALB/c mouse. This strain according to reports is among
the most widely used inbred models used in biomedical research, and it is
particularly utilized in immunology and infectious disease.
Prof. Matovu said
that the mice are going to come from United States of America after
Uganda’s initial attempts to get them from China did not yield fruit.
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MP Awany encouraged
the researchers to always update the country about the progress of their work
so that the public is not kept in the dark.
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Musenero welcomed the
advice saying that they will build on their communication.